About No. 1 evidence-based POC saliva diagnostics
About dentognostics No. 1 evidence-based POC saliva diagnostics
dentognostics
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About us
dentognostics GmbH
The research and development technology company dentognostics GmbH has been in existence for more than 20 years and specialises in the analysis of saliva in real time at the point of care. The goal: healthy people should stay healthy. The US market leader holds more than 40 patents worldwide and, with more than 400 studies on the biomarker aMMP-8, offers the most scientifically documented predictive saliva diagnostics in the world for the early detection of collagen degradation processes in the body, especially in the mouth. The technology made in Germany is used by leading providers in the medical field to keep patients healthy.
Customers and partners of dentognostics include leading dental chains worldwide, leading space organisations such as NASA and ESA as well as the M.A.R.S. simulation study. Renowned football clubs and successful competitive athletes also work with the diagnostics. Due to the predictive nature of its technology, dentognostics is the first step and first choice for every (dental) practice and for every institution that deals with molecular diagnostics and/or wants to rely on systemic screening.
‘aMMP-8 technology is the breakthrough for proactive dentistry and oral-systemic health.’
Prof. Dr. Dr. Andreas Pfützner
President of the German Oral Health Foundation
Diabetologist & laboratory physician

Milestones 2025
World record: aMMP8 test campaign in the UK
The first world record for a mass test was recently achieved.
WHO targets focus on oral health
In its global action plan for oral health, the WHO has set the targets for 2030. The oral health goals are the absolute priority:
- Caries and periodontitis prevention
- Protection against tooth loss
To achieve this, the WHO has also formulated the promotion of preventive measures and the sensitisation and education of the population as goals.
Launch of own Academy
Training our customers is at the heart of our practice quality management. Our online academy is now available to you with 24/7 access to high-calibre seminars and on-demand courses.
Prevention Heroes
We are supporting the German Oral Health Foundation's latest campaign ‘Prevention Heroes’. Based on the WHO action plan, the Health Senate of the German Oral Health Foundation (DMS) has developed its own action plan. This includes the topic of ‘systemic screening with predictive biomarkers’.
M.A.R.S. simulation study
In 2024, dentognostics joined the research project of the M.A.R.S. team (Mars Analogue Research Simulation) of the Université catholique de Louvain/Belgium for its upcoming mission. Due to the high relevance of the topic, we were also invited to accompany the M.A.R.S. simulation study in April with our in-vitro diagnostics for 2025.
Our mission
The Future of Oral Health
Revolutionizing Pro-Active Dentistry
Discover our top products now
ORALyzer® Expert has been used successfully all over the world to date
and more are being used every day.
Good oral health is the basis for good general health and optimum performance. Hundreds of studies have proven the importance of oral health for increasing performance and improving physical well-being.
Customizing
dentognostics offers customised software implementation solutions for dental chains and major providers. Integration & control of reader systems directly from the patient management system. Contact us to discuss your customised project.
Quality management
The dentognostics product range is authorised and registered as a medical device in Europe, the UK and Switzerland. It is also certified in accordance with EN ISO 13485:2016.

WHO goals by 2030
In its global action plan for oral health, the WHO has set the targets for 2030. The oral health goals are the absolute priority:
- Caries and periodontitis prevention
- Protection against tooth loss