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WHO: "Virtually all countries must build up a monitoring system to control the spread of periodontitis and promote oral health." From: Strengthening the prevention of periodontal disease: The WHO approach

Prof. Dr. Thomas Hoffmann: "Periodontitis and peri-implantitis must […] become avoidable diseases. Early diagnostics and prophylaxis do play a decisive role here. In diagnostics, aMMP-8 could become a key technology in the process in the near future."

The WHO is focusing activities in the 21st century on oral health and the struggle against periodontitis. The weapon for this battle could be the aMMP-8 diagnostics.

Periodontitis significantly increases the risk for diabetes, cardio vascular illnesses, rheumatism and premature births. An early diagnosis can help to stop the process.

Dentognostics
+++ The enzyme aMMP-8 may provide an open gate for the bacteria to enter the bloodstream +++ The PerioMarker® rapid test reveals hidden inflammations +++ The aMMP-8 Rapid Test takes less than ten minutes +++ dentognostics offers high-efficiency products at the interface of medicine and dental medicine +++

PerioSafe® aMMP-8 Rapid Test Home

 

The PerioSafe® aMMP-8 Rapid Test Home is a special mouth rinse rapid test to analyze the risk of collagenolytic activity in the oral cavity. The test was designed for use at home by the patient. The test is currently under development.

The PerioSafe® aMMP-8 Rapid Test Home uncovers concealed inflammations with periodontal tissue destruction using the biomarker aMMP-8. The test can help the end-user find hitherto undetected periodontal inflammations.

The rapid test ascertains the active matrix-metallproteinase-8 (aMMP-8), a biomarker for collagenolytic activity. The aMMP-8 proof is delivered in less than 10 minutes and is determined from a rinse from the oral cavity. The rapid test can therefore be performed in under ten minutes at home.

Increased aMMP-8 values suggest active inflammatory processes in the periodontium, indicating periodontitis. If untreated, these inflammations can lead to tooth loss and are considered a gateway for oral bacteria to enter the blood stream. Thanks to the PerioSafe®, patients can find out whether their body is suffering from active inflammatory processes that might significantly increase the risk of diabetes, cardio-vascular diseases, rheumatism, arthritis, or premature birth.

The test is manufactured by dentognostics and will be sold by pharmacies, drug stores, on the Internet and via direct sales marketers.

PerioSafe® aMMP-8 Rapid Test Home is currently in development. Market introduction in 2012.

 

 
 

The PerioMarker®

rapid test reveals hidden inflammations. It can identify the risk even before any clinical signs become visible, such as irreversible destruction of periodontal tissue and jawbones or loosening of teeth.

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aMMP8 degrades tissue

An aMMP-8 rapid test is especially effective in indicating previously concealed periodontal inflammations in at-risk groups. And early detection means that preventive measures can be taken before symptoms set in.

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Few patients know,

that an inflammation in the mouth can increase significantly the risk of such serious diseases as heart attack, apoplectic stroke and diabetes.

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For physicians:
ORI Oral RiskIndicator aMMP-8 Rapid Test Professional